Moozek has dug up information on an upcoming plug-in manager application called Lok and Load. From their website:

Manage your Plug-Ins with Lok and Load -
Lok and Load is a Plug-Ins Manager. It is designed to work with Pro Tools. It also has the capability for handling other similar applications where configuration for VST or DX type Plug-Ins is desired.

Speeds Pro Tools Startup Time -
Lok and Load speeds up your application load time by filtering out any Plug-Ins that you don’t want to use for a session. Additionally, it makes selection of Plug-Ins during your session less cluttered.

I guess if you don’t use Waves then you can just move the plug-ins to the unused folder (I moved 10-15 today!).

Multiple Plug-Ins Configurations -
Lok and Load allows you to have multiple “Plug-Ins configurations” and these can easily be edited to obtain the perfect Plug-Ins set for each purpose.

Quick Access Desktop Shortcuts -
Lok and Load creates Desktop Shortcuts. This means you can launch your application directly and have a Plug-Ins configuration automatically applied in the same process.

This on the other hand sounds interesting IMO.

Lok and Load website

Via post on Moozek